Germfree mice survive thermal trauma better than conventional mice. Mortality during the first 48 hr (shock mortality) after severe (95 C) and moderate (70 C) hot-water burns was significantly less in germfree animals than in conventional controls. Mortality after 48 hr (late mortality) was significantly reduced in germfree mice after a moderate burn. These experiments, together with the previous finding of gram-negative bacteria in the tissues of conventional burned mice, demonstrate that bacteria cause death in burned mice during the shock period as well as later.
- shock mortality after burns
- late burn mortality
- infection in burns
- Copyright © 1965 by American Physiological Society