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Am J Physiol 209: 283-286, 1965;
0002-9513/65 $5.00
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Reliability of inulin for determining volume flow in rat renal cortical tubules

Donald Marsh 1 and Charles Frasier 1

1 Department of Physiology and Biophysics, New York University School of Medicine, New York City

The recovery of inulin was complete when perfused by micropuncture into single proximal tubules and collected from the corresponding distal tubule. Systemic infusion of inulin during similar experiments revealed no inulin secretion. Inulin-C14 was completely recovered in the urine when injected into single proximal tubules. These experiments provide direct affirmation of the assumption that inulin is conserved in the tubule lumen.

Key Words: inulin conservation • tubular volume flow • tubular microperfusion

Submitted on March 9, 1965







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Copyright © 1965 by the American Physiological Society.