AJP Legacy Add DOIs to your references at manuscript stage!
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol 208: 1119-1128, 1965;
0002-9513/65 $5.00
This Article
Right arrow Full Text (PDF)
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Marsh, D. J.
Right arrow Articles by Solomon, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Marsh, D. J.
Right arrow Articles by Solomon, S.

Analysis of electrolyte movement in thin Henle's loops of hamster papilla

Donald J. Marsh 1 and Sidney Solomon 1

1 Department of Physiology and Biophysics, New York University School of Medicine, New York City, and Physiologisches Institut der Freien Universität Berlin and Gottingen, Germany

Saline solutions isolated between oil droplets within the lumen of thin limbs of Henle's loops remained at constant volume, while raffinose solutions underwent a continuous volume increase with time. After equilibrium, composition of the NaCl perfusates with respect to osmolality and Na and Cl concentrations became similar to that of vasa recta plasma. These results were identical for both ascending and descending limbs and suggest that neither segment transports salt actively. Descending limbs and vasa recta were isopotential under all conditions; the ascending limb during antidiuresis is 9 mv negative, the collecting ducts 17 mv negative. Ascending limb negativity was abolished by osmotic diuresis or stopped-flow microperfusion with saline. Measurement of ion concentrations showed that the ascending limb potential of antidiuresis is not a diffusion potential, and that its disappearance during osmotic diuresis is not due to the appearance of a diffusion potential of countersign. We suggest that the ascending limb potential is a streaming potential, but that the collecting duct potential reflects active ion transport.

Key Words: loops of Henle • countercurrent system • urinary concentrating mechanism • collecting ducts • active ion transport • tubular fluid ion concentration • tubular fluid osmolality • tubular microperfusion • streaming potentials • diffusion potentials

Submitted on September 15, 1964




This article has been cited by other articles:


Home page
 Am. J. Physiol. Renal Physiol.Home page
T. L. Pannabecker
Loop of Henle interaction with interstitial nodal spaces in the renal inner medulla
Am J Physiol Renal Physiol, December 1, 2008; 295(6): F1744 - F1751.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
T. L. Pannabecker, W. H. Dantzler, H. E. Layton, and A. T. Layton
Role of three-dimensional architecture in the urine concentrating mechanism of the rat renal inner medulla
Am J Physiol Renal Physiol, November 1, 2008; 295(5): F1271 - F1285.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
A. T. Layton, T. L. Pannabecker, W. H. Dantzler, and H. E. Layton
Two modes for concentrating urine in rat inner medulla
Am J Physiol Renal Physiol, October 1, 2004; 287(4): F816 - F839.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
M. A. Knepper, G. M. Saidel, V. C. Hascall, and T. Dwyer
Concentration of solutes in the renal inner medulla: interstitial hyaluronan as a mechano-osmotic transducer
Am J Physiol Renal Physiol, March 1, 2003; 284(3): F433 - F446.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 1965 by the American Physiological Society.