Center of arterial pressure regulation during rotation of normal and abnormal dogs

¹ Department of Physiology and Biophysics, University of Mississippi, School of Medicine, Jackson, Mississippi

Dogs were rotated about a horizontal transverse axis. By shifting the axis of rotation along the length of the animal's body it was possible to find a point at which arterial pressure remained almost constant in all positions of rotation. In most normal dogs such an axis lay in the neck a few centimeters cephalad to the sternum. Denervation of carotid sinus and aortic pressoreceptors caused a caudal shift of the axis; total spinal anesthesia did also, and to a much greater degree. This study demonstrates that pressure regulatory mechanisms operate to maintain a constant arterial pressure in the neck, probably for the minimizing of postural alterations of cerebral blood flow

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