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Am J Physiol 204: 847-848, 1963;
0002-9513/63 $5.00
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Effect of histamine on adrenal 17-hydroxycorticoid secretion in unanesthetized dogs

Tatuzi Suzuki 1, Kenji Hirai 1, Haruhiko Yoshio Ken-Ichi Kurouji 1, and Kazukuni Yamashita 1

1 Department of Physiology, Nagasaki University School of Medicine, Nagasaki, Japan

Dogs with previously sectioned dorsal spinal roots (T11-L3) were used in experiments for collecting the adrenal venous blood without anesthetizing or evoking any pain. Intravenous injection of histamine in doses of 0.05–1.0 mg/kg body wt. was demonstrated to produce a marked acceleration of 17-hydroxycorticoid secretion. The time courses of changes in the secretion rate after injection of varying doses of histamine are compared.

Submitted on November 8, 1962




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 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
I. Matsumoto, Y. Inoue, K. Tsuchiya, T. Shimada, and T. Aikawa
Degranulation of mast cells located in median eminence in response to compound 48/80 evokes adrenocortical secretion via histamine and CRF in dogs
Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2004; 287(4): R969 - R980.
[Abstract] [Full Text] [PDF]


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