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Am J Physiol 204: 842-846, 1963;
0002-9513/63 $5.00
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Effect of oxytocin, vasopressin, and related peptides on plasma free fatty acids

I. Arthur Mirsky 1

1 Department of Clinical Science, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

A significant decrease in the concentration of the free fatty acids of the plasma of nondiabetic or alloxan-diabetic dogs was produced by the intravenous injection of oxytocin, desamino-oxytocin, 3-valine-oxytocin, 2-phenylalanine-oxytocin, arginine-vasopressin, lysine-vasopressin or 2-phenylalanine-8-lysine-vasopressin. The effect is dependent upon the integrity of the disulfide bridge of the various peptides and is attributed to an insulin-like action on adipose tissues.

Note:
With the Technical Assistance of Louisa C. Linn

Submitted on October 23, 1962






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