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1 Department of Physiology, University of Colorado School of Medicine, Denver, Colorado
Rats cool in high carbon dioxide at room temperatures from 12 to 41 C. Confinement plays only a small role in this cooling. The mechanisms for cooling appear to be: 1) lowered metabolic rate, 2) lack of shivering, 3) hyperventilation. High carbon dioxide administration is accompanied by intense peripheral vasoconstriction which, when room temperatures are higher than body temperatures, aids cooling.
Submitted on August 16, 1962
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