Effect of aldosterone administration on electrolyte excretion and GFR in the rat

¹ Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina

Two groups of rats were fed equal quantities of an electrolyte-free diet which was supplemented with potassium by gavage. One group received aldosterone in sesame oil and the other the vehicle by daily injection. The excretion of potassium was not influenced by the administration of aldosterone. In addition, there was no effect on the filtration rate or tissue electrolyte composition.