Renal excretion of magnesium in the rabbit

¹ Commissariat à l'Energie Atomique, Département de Biologie, Service Hospitalier Frédéric Joliot, Orsay, S. et O., France

In rabbits, after rapid intravenous injection of Mg²⁸, the plasma and urinary specific activities, corrected for transit time, are at all times in equilibrium. Injection of Mg²⁸ during stop flow does not reveal any tubular zone permeable to magnesium. On the other hand, the magnesium behavior is in many ways comparable to that of a glomerular substance. These three arguments lead to the view that urinary magnesium is of essentially glomerular origin, and rule out any mechanism of tubular exchange or secretion.

Note:
With the Technical Assistance of S. Ricard and M. Joly