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Am J Physiol 202: 465-468, 1962;
0002-9513/62 $5.00
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Blockage of lactation by brain-stem lesions in the cat

Carlos Beyer 1, Flavio Mena 1, Pablo Pacheco 1, and Manuel Alcaraz 1

1 Instituto de Estudios Médicos y Biológicos, Universidad Nacional Autonoma, Ciudad Universitaria, México, D. F.

The effect of brain-stem lesions on lactation in the cat was studied. Lesions in the rostral mesencephalon or caudal hypothalamus, which involved the dorsal longitudinal fasciculus, caused persistent supression of milk secretion and involution of the mammary glands. This effect seems to be due to interruption of the afferent pathway for prolactin secretion. Control lesions in other parts of the brain caused only a transient impairment of lactation.

Submitted on August 14, 1961






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