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Am J Physiol 201: 363-364, 1961;
0002-9513/61 $5.00
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Creatine, creatinine, and creatine phosphate in normal and hypertrophied rat hearts

E. C. Gangloff 1, I. L. Hemmings 1, and R. F. Krause 1

1 Department of Biochemistry, West Virginia University Medical Center, Morgantown, West Virginia

Cardiac hypertrophy was produced in adult, male, albino rats by exercise. A highly significant increase in creatine phosphate and percentage of creatine as creatine phosphate in cardiac hypertrophy was demonstrated. No significant differences were detected in creatine or creatinine concentrations.

Submitted on February 7, 1961




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