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Am J Physiol 201: 349-350, 1961;
0002-9513/61 $5.00
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Effect of hemorrhage on LD100 of dog following supralethal dose of total body gamma radiation

Stanley W. Handford 1 and Paul W. Johnson 1

1 Naval Medical Research Institute, National Naval Medical Center, Bethesda, Maryland

To test the effect of hemorrhage on survival following wholebody exposure to a supralethal dose of radiation, three groups of dogs were bled 25% of their estimated blood volume. In group 1, bleeding was accomplished immediately before irradiation; in groups 2 and 3, 30 min and 48 hr, respectively, following irradiation. No significant alterations in the course of acute radiation sickness or survival time (LD100) were observed.

Note:
With the Assistance of Robert J. Scholtes and Marshall S. Duny

Submitted on February 1, 1961






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