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Am J Physiol 200: 703-706, 1961;
0002-9513/61 $5.00
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Temperature regulation of rats with hypothalamic hyperphagia

Paul W. Han 1 and John R. Brobeck 1

1 Department of Physiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

Temperature regulating mechanisms of rats with ventromedial lesions of the hypothalamus were studied by determining their body temperature responses to exercise, and to exposure to cold or heat. These lesions caused no primary impairment of temperature regulation. A higher body temperature observed after forced exercise was found to be secondary to the rats' hyperphagic behavior and their consequent weight gain.

Submitted on August 18, 1960







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