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1 Neurosurgical Research Laboratory of Children's Hospital; and Department of Surgery, Harvard Medical School, Boston, Massachusetts
The cerebral oxygen consumption of monkeys (Macaca mulatta) has been measured with the animals' rectal temperatures varying from 19° to 37° C. The animals were allowed to remain at the experimental temperature for 1 hour before oxygen consumption studies were done. Cerebral oxygen consumption was calculated using the Kety-Schmidt nitrous oxide technique for measuring cerebral blood flow. A linear relationship was found between the logarithm of the cerebral oxygen consumption and the reciprocal of the absolute temperature (°K) of the body. This held over the entire temperature range studied with a standard deviation about equal to that of the method for measuring the cerebral oxygen consumption.
Submitted on July 29, 1960
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