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Am J Physiol 200: 133-134, 1961;
0002-9513/61 $5.00
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Potassium efflux from isolated rabbit heart into a potassium-free solution

E. W. Humphrey 1

1 Department of Surgery, Veterans Administration Hospital; and the University of Minnesota, Minneapolis, Minnesota

The efflux of potassium from the isolated perfused rabbit heart into a potassium-free solution has been calculated from the zero time slope of the washout curve and the initial potassium concentration. It was found that this efflux very closely approximated that calculated from the K42 equilibration curves. Increasing the calcium content of the perfusate twofold had no significant effect on the outflux of potassium.

Submitted on August 4, 1960






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