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Am J Physiol 198: 571-574, 1960;
0002-9513/60 $5.00
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Magnesium excretion in the dog studied by stop-flow analysis

H. V. Murdaugh JR. 1 and R. R. Robinson 1

1 Department of Medicine, University of Alabama Medical School; and Medical and Radioisotope Services, Veterans Administration Hospital, Birmingham, Alabama

Stop-flow analysis performed in the dog using Mg-28 demonstrated active reabsorption of magnesium in the proximal portion of the distal nephron. ‘Interrupted’ stop-flow analysis failed to document the existence of a renal tubular secretory mechanism for magnesium. During magnesium-loading reabsorption of potassium occurs in the distal nephron despite the presence of hyperkalemia.

Note:
With the Technical Assistance of R. E. Galloway, E. H. Hayes and B. H. Williams

Submitted on October 7, 1959






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