Absorption of 3-methylglucose from the intestine of the frog, Rana pipiens

¹ Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina

The rate of absorption of 3-methylglucose from the intestine of the frog (Rana pipiens) is lower than that of d-glucose but higher than that of d-xylose. The rate of absorption of 3-methylglucose depends on the temperature. The percentage of absorbed 3-methylglucose and that of glucose decreases with the increase in the initial intestinal sugar concentration. In case of d-arabinose and d-xylose such a relationship cannot be established. 3-Methylglucose is transported in vitro from the mucosal compartment into the serosal compartment against a gradient at 30°C but not at 0°C. l-Glucose is not transported against a gradient at 30°C.

Note:
With the Technical Assistance of O. Jean Seal