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Am J Physiol 197: 1317-1321, 1959;
0002-9513/59 $5.00
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Absorption and distribution of S35O2 inhaled through the nose and mouth by dogs

Oscar J. Balchum 1, Jerzy Dybicki 1, and George R. Meneely 1

1 Vanderbilt University Medical School and Hospital, Nashville, Tennessee

Dogs breathing S35O2 through the nose and mouth retained a smaller proportion of the inhaled gas in the trachea, lungs, hilar lymph nodes, and liver and spleen than those breathing similar concentrations via a tracheostomy. This conclusion is substantiated by tissue S35 concentration assays, and measurements of the compliance of the lungs and thorax, and of pulmonary resistance. The upper airways therefore partially protect the lungs from exposure to sulfur dioxide.

Submitted on June 1, 1959







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Copyright © 1959 by the American Physiological Society.