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Am J Physiol 197: 671-673, 1959;
0002-9513/59 $5.00
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Effects of cholesterol and ß-sitosterol in the gerbil

Samuel Gordon 1, Sidney J. Stolzenberg 1, and Walter P. Cekleniak 1

1 Lederle Laboratories, Division of American Cyanamid Company, Biochemistry Department, Biochemical Research Section, Pearl River, New York

The effect of increasing levels (0–1.0%) of dietary cholesterol has been studied in the Mongolian gerbil. A consistent and proportional elevation of serum cholesterol was observed after one week of cholesterol administration. In addition, the simultaneous administration of ß-sitosterol prevented this hypercholesteremia.

Submitted on May 28, 1959






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