Effects of different frequencies of stimulation of sciatic nerves on the patellar reflex

¹ Department of Pharmacology and Chemotherapy, Armour Laboratories, Kankakee, and Stritch School of Medicine, Loyola University, Chicago, Illinois

The patellar reflex was recorded every 10 seconds in cats under high cervical spinal section. The effects of different frequencies of electrical stimulation on both the ipsilateral and contralateral sciatic nerves were studied. At frequencies of 1–10/sec., contralateral sciatic nerve stimulation produced a depression of the patellar reflex. Frequencies of 20–120/sec. produced augmentation of the reflex. Stimulation of the ipsilateral sciatic nerve, through the same range of frequencies, only produced a gradient depression of the patellar reflex. The effect of pentobarbital on these reflexes in the same type of high cervical spinal cat was noted. The effects of frequency of stimulation, as well as anesthetic used, must be considered in using this reflex preparation.