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Am J Physiol 197: 34-36, 1959;
0002-9513/59 $5.00
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Effects of cold acclimation on hepatic carbohydrate and lipid metabolism

J. M. Felts 1 and E. J. Masoro 1

1 Department of Physiology, Tufts University School of Medicine, Boston, Massachusetts

The acclimation of rats to low environmental temperatures was found to alter the hepatic metabolic response to fasting for 1 day at 0–2°C. Liver glycogen was stabilized, fatty infiltration of the liver did not occur and liver slices were better able to oxidize acetate-I-C14 and palmitate-I-C14 to C14O2. These results provide an excellent example of an acclimation process occurring at the molecular level.

Note:
With the Technical Assistance of Ann Wertheimer

Submitted on December 9, 1958






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