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1 Department of Cardiorespiratory Diseases, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D.C.
The physiology of hydropenia was studied in cats and dogs placed on three regimens: 1) no waterno food; 2) water ad libitumno food; and 3) no waterfood. Animals deprived of water and food show elevations in plasma sodium, chloride, osmotic pressure and total solids, with progressive hydropenia. Tap water ad libitum prevents these changes in fasting and promotes slight decreases in plasma osmotic pressure; it also sustains life well beyond the period endured by animals with no access to fluid. That cats with no drinking fluid are able to maintain themselves well for long or indefinite periods on diets of cod, salmon and beefsteak, and are unable to do so on partly desiccated salmon and beef, is generally predictable by metabolic calculations and confirmed by measurements. The significance of these facts for the water metabolism of marine mammals which may not drink is broached.
Submitted on July 23, 1958
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