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Am J Physiol 195: 659-662, 1958;
0002-9513/58 $5.00
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Effects of Thermal Injury and of Skin Removal on Thyroid Function in the Rat

Seymour Reichlin 1 and Zelig H. Lieberman 1

1 From the Departments of Psychiatry and Medicine and the Department of Surgery, Washington University, St. Louis, Missouri

Thyroid I131 release rates have been measured in 6 rats before and after a 10–20% full thickness burn of the skin, and in 11 rats before and after resection of 10–20% of the dorsal skin surface. Thyroid function was inhibited for a variable period up to 30 hours after the burn in five of six animals. In contrast, flaying was followed in each of the 11 rats by increased thyroid function.

Submitted on April 6, 1958






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