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Am J Physiol 195: 448-450, 1958;
0002-9513/58 $5.00
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Failure of Change in Extracellular Volume to Alter Plasma Potassium Concentration

Belding H. Scribner 1, Henry Kleinberg 1, and James M. Burnell 1

1 From the Veterans Administration Hospital, Seattle, and the Department of Medicine, University of Washington, Seattle, Washington

Changes in the plasma potassium concentration have been attributed to changes in extracellular space volume. The extracellular space of dogs was increased by 53%; the plasma potassium concentration fell only during the transient disequilibrium state. It is concluded that the plasma potassium concentration is independent of the size of the extracellular space.

Submitted on November 24, 1957






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