Hemostasis in Dogs With Heart-Lung By-Pass Circulation

¹ From the Laboratory of Haematology, Instituto Oswaldo Cruz, Rio de Janeiro, Brasil

Heart-lung by-pass circulation obtained in dogs by an apparatus improvised in the laboratory has shown that from the very beginning of the circulation outside the lung the bleeding time increased greatly. The return to normal circulation in the animal after the experiment showed that the hemostasis returns to its normal figure from 30 to 60 minutes afterwards. This observation agrees with prior observations on the different behavior of venous and arterial blood as far as its capacity for hemostasis is concerned, and is in accordance with the increased hemostatic capacity of blood once passed through a heart-lung preparation—all these facts indicating the existence of a lung function in the control of ordinary hemostasis.