Hypercholesteremic Effect of Various Phospholipid Preparations

¹ From the Harold Brunn Institute, Mount Zion Hospital, San Francisco, California

Twelve phosphatide preparations from vegetable, animal, yeast and synthetic sources were infused intravenously into normal or functionally hepatectomized rats at such a rate as to maintain plasma phospholipids at 2–10 times normal levels over a period of 6–24 hours. Consequent upon such infusion, plasma cholesterol concentration rose significantly. All preparations were active in greater or lesser degree, with the exception of duck egg lecithin.

Note:
with the technical assistance of Joanne Jepson, Toy Der, Clarence Omoto, Betty Tsai and Judith Levy