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Am J Physiol 193: 89-91, 1958;
0002-9513/58 $5.00
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Age Related Changes in Plasma Proteins of the Fetal Goat

Joseph J. Barboriak 1, Gregorio de Bella 1, Ivo Setnikar 1, and Willard A. Krehl 1

1 From the Department of Biochemistry, Yale Nutrition Laboratory and the Department of Physiology, Yale University School of Medicine, New Haven, Connecticut

Changes in the protein composition of the fetal plasma of the goat as related to the age of the fetus were followed by means of paper electrophoresis. Five protein peaks could be distinguished and they were tentatively marked as albumin, fetuin, alpha1, alpha2 and beta globulins. Practically no gamma globulins were detected. The plasma albumin relative concentration increased from 6% on the 46th day to 45% on the 135th day of gestation. The relative fetuin content decreased with the advancing age of the fetus. The percentage of alpha1, alpha2 and beta globulins did not change significantly during fetal development.

Submitted on October 29, 1957






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Copyright © 1958 by the American Physiological Society.