Influence of Testosterone Propionate on the Succinic Dehydrogenase Activity of Male Rat Liver

¹ From the Department of Physiology, Topiwala National Medical College, Bombay, India

Castration of male rats was shown previously to cause an increase of the succinic dehydrogenase activity in male rat liver homogenate. The present study was undertaken to examine if this increase was influenced by testosterone administration to the castrated animals over different periods of duration. It was observed that testosterone treatment counteracted the increase in the enzyme activity caused by castration and that this effect was more marked with longer duration of the hormone administration. Further the succinic dehydrogenase activity was not related directly to the wet weight of the liver.