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Am J Physiol 192: 572-576, 1958;
0002-9513/58 $5.00
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Sensitivity of Paramecium Caudatum to High Oxygen Tensions and Its Modification by Cobalt and Manganese Ions

Rebeca Gerschman 1, Daniel L. Gilbert 1, and Justin N. Frost 1

1 From the Department of Physiology, The University of Rochester School of Medicine and Dentistry, Rochester, New York

Paramecia were put in a hanging drop in a special chamber in which they could be observed under the microscope while they were exposed to different pressures of oxygen. Characteristic morphological changes were recorded photographically and were found to be very similar to changes induced by radiation. Survival times decreased from 8.05 hours at 2 atm. to 0.87 hours at 20 atm. of pO2. Treatment with cobalt (II) chloride and manganese (II) chloride (m/200,000) increased the survival times at 9 atm. and decreased them at 2 atm. pO2.

Submitted on May 8, 1957







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