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Am J Physiol 192: 453-456, 1958;
0002-9513/58 $5.00
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Reversible Heat Block of Electrical Activity in the Goldfish Brain

Jean A. Cerf 1, Leon S. Otis 1, and Sadayuki F. Takagi 1

1 From the Division of Psychiatry, Neuropsychiatric Institute, University of Illinois College of Medicine, Chicago, Illinois

The effect of temperature elevation on the electrical activity of the vagal lobe was studied in both intact and isolated goldfish brain. The slow potential changes recorded at room temperature ceased above a critical temperature (about 37°C), and reappeared on cooling. The degree of reversibility of the block was inversely proportional to the duration of heat application and the final temperature of the brain immediately preceding cooling.

Submitted on December 18, 1956






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