Carbohydrate Metabolism in Rats With Acute Uremia

¹ From the Department of Medicine, Peter Bent Brigham Hospital and Harvard Medical School, Boston, Massachusetts

To define areas of carbohydrate metabolism which might be altered in uremia, determinations of gastric and intestinal absorption of glucose and deposition of glycogen in the liver of 9 acutely uremic and 24 control rats were performed. Residual gastric and intestinal glucose contents and hepatic glycogen contents were determined 3 hours after glucose lavage in rats fasted for 24 hours. No statistically significant difference was observed in gastrointestinal absorption of glucose and in hepatic deposition of glycogen of the uremic and control animals.