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Am J Physiol 192: 157-163, 1957;
0002-9513/57 $5.00
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Hemodynamic Determinants of Coronary Flow: Effect of Changes in Aortic Pressure and Cardiac Output on the Relationship Between Myocardial Oxygen Consumption and Coronary Flow

E. Braunwald 1, S. J. Sarnoff 1, R. B. Case 1, W. N. Stainsby 1, and G. H. Welch JR. 1

1 From the Laboratory of Cardiovascular Physiology, National Heart Institute, Bethesda, Maryland

Although the general dependence of coronary flow on myocardial qo2 was confirmed in an in situ heart preparation, changes in aortic pressure and cardiac output were observed to be capable of influencing this relationship. Neither myocardial qo2 nor coronary flow were found to be dependent on left ventricular filling pressure.

Submitted on June 26, 1957






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