Effect of Long-Lasting Epinephrine on Serum Lipid Levels

¹ From the Department of Biochemistry, Medical Research Institute, Michael Reese Hospital, Chicago, Illinois

The injection of long-lasting epinephrine into dogs was followed in 1 hour by a rise in the concentration of serum triglycerides that was sustained for 24 hours. The concentrations of serum lipid phosphorus and cholesterol, however, were not perceptibly altered for the first 6 hours after the injection but were consistently elevated at the 24-hour period. Single injections of hydrocortisone, cortisone acetate or ACTH did not raise the serum concentration of lipid phosphorus or cholesterol in the 24-hour period after their injection. The triglyceride fraction did not rise significantly after cortisone or ACTH but did in some dogs receiving hydrocortisone.

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