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Am J Physiol 190: 13-16, 1957;
0002-9513/57 $5.00
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Effect of Dose Rate on Iron Incorporation Into Newly Formed Erythrocytes of Rats Exposed to Gamma Radiation

Siegmund J. Baum 1 and Donald J. Kimeldorf 1

1 From the U. S. Naval Radiological Defense Laboratory, San Francisco, California

Rats were subjected to 240 r gamma radiation at several dose rates (10 r/hr., 30 r/hr., 60 r/hr. and 120 r/hr.). At various days postradiation the animals were injected with radioactive iron and the appearance of the isotope in newly formed erythrocytes was measured in the circulation until it reached a maximum. Lowest Fe59 uptake was noted in animals injected with the isotope 24 hours postradiation. It was observed that dose rate influenced inversely the extent of iron incorporation during the recovery phase.

Submitted on February 19, 1957






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