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Am J Physiol 189: 475-478, 1957;
0002-9513/57 $5.00
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Metabolic Response of Dogs to Hypoxia in the Absence of Circulating Epinephrine and Norepinephrine

Nicholas M. Greene 1 and Ann D'E. Phillips 1

1 From the Section of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut

The importance of epinephrine and norepinephrine in the etiology of the metabolic effects of hypoxia is emphasized by the observation that dogs incapable of releasing these substances showed significantly less change in blood lactate and potassium during forced ventilation with 2.7% oxygen than did control dogs.

Submitted on January 21, 1957






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