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Am J Physiol 188: 355-359, 1957;
0002-9513/57 $5.00
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Effect of Body Temperature on Pulmonary Gas Exchange

A. B. Otis 1 and James Jude 1

1 From the Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland

Measurements were made of the arterial-alveolar carbon dioxide gradient in anesthetized dogs at body temperatures ranging from normal down to 16°C. Pulmonary diffusing capacity was determined by a steady-state carbon monoxide method in anesthetized dogs at normal body temperatures and at 25°C. From the results it is concluded that although diffusing capacity is reduced at low body temperatures, it is still adequate for transfer of both CO2 and O2 because the metabolic requirements for gas exchange are also reduced.

Note:
with the technical assistance of Roland Folse and Catherine Howard

Submitted on August 16, 1956







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Copyright © 1957 by the American Physiological Society.