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Am J Physiol 187: 473-478, 1956;
0002-9513/56 $5.00
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Use of Electrical Currents to Delay Intravascular Thrombosis in Experimental Animals

Philip N. Sawyer 1 and Bernhard Deutch 1

1 From the Harrison Department of Surgical Research, Schools of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

Previous studies on the relationship of electric phenomena to intravascular thrombosis have been discussed. On the basis of these studies, canine experiments were designed to determine whether or not a negatively charged electrode could by means of its oriented current prevent formation of a thrombus in an injured vessel. Using electrodes of several types a series of controlled experiments were performed which demonstrate that a current created by the technique used would delay intravascular thrombosis for periods up to 12 hours.

Note:
with the technical assistance of Jonell Mayers

Submitted on January 16, 1955







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Copyright © 1956 by the American Physiological Society.