Muscle and Liver Glycogen of Mouse Strains Susceptible or Resistant to Nutritionally Induced Obesity

¹ From the Department of Biology, Brown University, Providence, Rhode Island

Muscle and liver glycogen levels of mice differing in their susceptibility to nutritionally induced obesity were studied in relation to inherited differences in metabolic and endocrine patterns. The I/Fn strain, resistant to nutritional obesity, is characterized by a muscle glycogen level four to six times higher than those of strains which can be made obese. The liver glycogen of the I strain mouse is significantly lower than those of the other strains. Muscle glycogen levels were found to reach a maximum at about 6 months of age in all but one of our strains.