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Am J Physiol 187: 160-162, 1956;
0002-9513/56 $5.00
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Effects of Graded Doses of Whole-Body X-Irradiation on Mast Cells in the Rat Mesentery

F. P. Conte 1, G. S. Melville JR. 1, and A. C. Upton 1

1 From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee

Male Sprague-Dawley rats were exposed to lethal and sublethal doses of x-radiation, and changes in the number of mast cells in the mesentery were correlated with dose and time postirradiation. After 75 r of whole-body x-radiation, a transient increase during the first 24 hours, followed by a slight decrease, in number of mast cells was observed. After larger doses of radiation (150–600 r), the mast cells were not seen to increase, but only to decrease in number during the first 2 weeks after exposure.

Submitted on December 13, 1955






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