Seminal Vesicle Growth as a Function of Androgen Stimulation in Mice

¹ From the Roscoe B. Jackson Memorial Laboratory, Bar Harbor, Maine

One hundred fourteen mice castrated at weaning were given different dosages of testosterone propionate by daily subcutaneous injection for 20 days. The seminal vesicle weight was chosen as the quantitative indicator of growth response in secondary sex organ. Thirty-four noncastrates were used for comparison. The growth of the seminal vesicles in response to the different dosages of hormone stimulation was shown, as are population growths, to be well fitted with the logistic curve. It was found also that the point of inflection of the dose-response curve was at a seminal vesicle weight which was close to the seminal vesicle weight of the untreated controls.

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