Influence of Epinephrine and Norepinephrine on Respiratory Variations in Vascular Pressures

¹ From the Department of Physiology and the Cardiovascular Laboratory, College of Medicine, State University of Iowa, Iowa City, Iowa

Comparisons were made between the respiratory variations in right and left ventricular and femoral arterial pressures of anesthetized dogs before and after the administration of l-epinephrine and l-norepinephrine. These analyses revealed significant deviations from control patterns following administration of these pressor drugs, but only at isolated points in the respiratory cycle. Many of these alterations could only be explained on the basis of alterations in cardiac and/or vasomotor activity.