Development of Acute Pulmonary Edema and Death in Dogs With Aortic Insufficiency Following Renal Artery Constriction

¹ From the Departments of Physiology and Pathology, College of Medicine, Howard University, Washington, D. C.

A standardized type of experimental aortic insufficiency was produced in dogs by partial removal of the aortic ‘noncoronary’ valve. A transventricular approach was used to perform the valvulectomies. All dogs with this type of aortic insufficiency, when subjected to renal artery constriction died in 2 days on the average with acute massive pulmonary edema and congestion.

Note:
with the assistance of Eula R. Hawthorne