AJP Legacy Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol 185: 71-76, 1956;
0002-9513/56 $5.00
This Article
Right arrow Full Text (PDF)
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Baumann, E. J.
Right arrow Articles by Seidlin, S. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Baumann, E. J.
Right arrow Articles by Seidlin, S. M.

Behavior of the Thyroid Toward Elements of the Seventh Periodic Group

Emil J. Baumann 1, Norma Z. Searle 1, A. Aaron Yalow 1, Edward Siegel 1, and S. M. Seidlin 1

1 From the Medical Physics Laboratory, the Medical Division, and the Laboratory Division, Montefiore Hospital, New York City

In order further to test our hypothesis that the elements of group VII are selectively filtered from the blood and concentrated by the thyroid gland, rats were injected with Mn54, Br82 and Tc99. The distribution of these nuclides in tissues was determined 2 hours after administration. The thyroidal concentration of Mn54 was about 10 times that of serum, of Br82 1.3 times that of blood and of Tc99 11–30 times that of blood. These results together with those previously reported by us and by others show that ions of all group VII elements are concentrated by the thyroid, though to a varying extent. A study of the effect of stable seventh group ions on the uptake of Mn54, Br82, I131 and Re186 shows that large amounts of F–, Mn++ and Br– have little influence while even small quantities of I– or of Re++ markedly lower the thyroidal uptake of the heavier ions. Only a slight affinity of the thyroid for F–, Mn++, Br– is thus indicated, while that for I– and Re++ is far greater. This conclusion is substantiated by another type of experiment in which pairs of these nuclides were administered simultaneously and the fraction of each taken up by the thyroid determined. The affinity of the thyroid for Te, I and Re proved to be roughly equal and much larger than for Mn or Br. Unlike other group VII elements Mn accumulates in tissues of endodermal origin to an even greater extent than in the thyroid.

Submitted on October 11, 1955




This article has been cited by other articles:


Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
N. Tran, L. Valentin-Blasini, B. C. Blount, C. G. McCuistion, M. S. Fenton, E. Gin, A. Salem, and J. M. Hershman
Thyroid-stimulating hormone increases active transport of perchlorate into thyroid cells
Am J Physiol Endocrinol Metab, April 1, 2008; 294(4): E802 - E806.
[Abstract] [Full Text] [PDF]

Home page
 Journal of the American Animal Hospital AssociationHome page
L. C. Paull, J. C. R. Scott-Moncrieff, D. B. DeNicola, N. Glickman, K. R. Refsal, and L. T. Glickman
Effect of Anticonvulsant Dosages of Potassium Bromide on Thyroid Function and Morphology in Dogs
J. Am. Anim. Hosp. Assoc., March 1, 2003; 39(2): 193 - 202.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 1956 by the American Physiological Society.