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Am J Physiol 184: 141-144, 1955;
0002-9513/55 $5.00
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Detection of Dietary Cholesterol-4-C14 in the Hepatic Reticulo-Endothelial Cell of the Rat

Meyer Friedman 1, Sanford O. Byers 1, and Shirley St. George 1

1 From the Harold Brunn Institute for Cardiovascular Research, Mount Zion Hospital, San Francisco, California

Separation and isolation of hepatic parenchymal from reticulo-endothelial cells of rats given cholesterol-4-C14 was accomplished. Radioactivity was found in both cell types 6 and 24 hours following oral administration, indicating that the reticulo-endothelial cells play a role in the disposition of dietary derived cholesterol.

Submitted on July 22, 1955






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